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The Arizona Diamondbacks (72-74) get their chance for immediate revenge as they take on the San Francisco Giants (74-71) in Wednesday’s 3:45 PM ET matinee at Oracle Park. After what happened in our last meeting, this feels like a statement game waiting to happen.
Game Details and Where to Watch
When: Wednesday, September 10, 2025 at 3:45 PM ET (12:45 PM local)
Where: Oracle Park, San Francisco
TV: NBC Sports Bay Area (NBCS-BA) and Arizona Sports (ARID)
Betting Lines Show Tight Contest
The oddsmakers can’t decide who to back in this one:
- Giants Moneyline: -114
- Diamondbacks Moneyline: -105
- Run Line: Diamondbacks -1.5 (+156)
- Total Runs: 8.5
Wait, what? We’re getting run line value at +156 while essentially being pick-em on the moneyline? That tells me the books respect our explosive offense but aren’t sure about the pitching matchup. I’ll take that action all day long.
Pitching Matchup: Experience vs. Unknown Quantity
Diamondbacks: Eduardo Rodriguez (7-8) makes his 26th start of the season
Giants: Carson Seymour (1-2) takes the ball for just his third start
This is where D-backs fans should feel confident. E-Rod has been around the block and knows how to pitch in big spots. Sure, his record doesn’t jump off the page at 7-8, but he’s been eating innings and keeping us competitive all season.
Meanwhile, the Giants are rolling the dice with Seymour, who’s made all of two starts this year. That screams opportunity for our lineup. When you’re facing a pitcher with limited MLB experience, you attack early and often.
D-backs Offensive Machine: Built for Oracle Park
The Numbers Don’t Lie: We rank 5th in MLB in runs scored (719) and 6th in home runs (198), while the Giants sit at 15th in runs (634) and 19th in homers (159). This isn’t even close offensively.
Our Lineup Card of Dreams:
- Corbin Carroll: Leading the way with 30 home runs and that game-changing speed
- Ketel Marte: Our steady veteran anchor hitting .283 and getting on base
- Geraldo Perdomo: Team-leading 91 RBIs from a guy who just keeps producing
- Gabriel Moreno: Young catcher showing he belongs with a .283 average
Here’s the thing about Oracle Park that people don’t understand – good hitters still find ways to drive in runs. Our .250 team batting average (10th in MLB) means we’re not just living and dying by the long ball. We can manufacture runs when the dimensions don’t cooperate.
Giants: Pitching Staff Carrying Limited Offense
Let’s give credit where it’s due – San Francisco has solid pitching. Their 3.75 team ERA (6th in MLB) keeps them competitive, and they strike out 8.6 per nine innings. But here’s the problem: they can’t score.
A .239 batting average (24th in MLB) and 4.4 runs per game tells the story. Rafael Devers has been their best hitter with 31 homers and 100 RBIs, but beyond him? Jung Hoo Lee leads the team in average at .271 but has just 8 home runs. That’s not going to cut it against quality pitching.
Why This Afternoon Game Favors Arizona
Afternoon baseball at Oracle Park is a different animal. The marine layer isn’t as thick, the wind patterns change, and visiting hitters often see the ball better in daylight. Our guys have been road warriors all season, and this setting should play right into our hands.
Plus, there’s something to be said for momentum in a series. We know what we’re capable of against this Giants team, and our offense has been clicking at the right time.
Injury Report: Both Teams Battling Depth Issues
The injury lists are long for both clubs, but we’ve shown all season we can overcome adversity. The Giants are dealing with their own issues, and frankly, their lineup doesn’t have the depth to absorb losses like ours does.
When you’re built around offensive firepower like we are, you can still score runs even when not at full strength. The Giants? They need every piece in place to generate offense.
Historical Context: D-backs Thrive as Road Underdogs
Check out these trends that should get every Diamondbacks fan excited:
- We’re 29-32 as underdogs this season (47.5% – better than expected)
- When getting similar odds to today, we’re 28-30 (48.3%)
- Meanwhile, the Giants are 46-39 when favored – good but not dominant
This team plays with house money when nobody expects us to win. That underdog mentality has served us well all year.
Keys to Victory at Oracle Park
- Jump on Seymour early – Inexperienced pitchers tend to struggle when pressured
- Carroll sets the tone – Our leadoff man needs to create chaos from pitch one
- Rodriguez attacks the strike zone – Don’t let their patient hitters work deep counts
- Take advantage of day game conditions – Better visibility means better contact
The Offensive Numbers That Should Scare San Francisco
Let me paint this picture clearly: we average 4.9 runs per game while they allow 3.75. That’s a recipe for offensive explosion. Add in the fact that they’re starting a pitcher with minimal MLB experience, and this could get ugly fast.
Our team ranks 10th in batting average while theirs ranks 24th. We strike out less (8.1 vs 8.5 per game) and hit for more power. The advanced metrics all point toward Arizona having a significant edge.
Why the Run Line Value is Too Good to Pass Up
Getting +156 on the Diamondbacks -1.5 when we’re essentially even money to win straight up? That’s the kind of bet you circle in red. Our explosive offense combined with their inexperienced starter creates the perfect storm for a multi-run victory.
Final Prediction from the Desert
This feels like one of those games where everything clicks for the D-backs. Rodriguez gives us quality innings while our offense feasts on a pitcher who’s in over his head at this level.
Oracle Park’s dimensions won’t matter when you’re squaring up fastballs from someone still learning to pitch at the major league level. Our lineup is too deep and too experienced to be shut down in a spot like this.
Predicted Final: Diamondbacks 9, Giants 4
Best Bet: D-backs run line -1.5 (+156)
Value Play: Over 8.5 runs
Bold Prediction: Carroll and Marte both homer
Sedona Red Revenge! Time to show the Bay Area what happens when you wake up a sleeping giant. Our offense is about to remind everyone why we’re one of the most dangerous teams in baseball. Let’s go D-backs!