How Do Antibiotics Work Against Bacteria?

Antibiotics are medications used to treat bacterial infections. These are also known as antibacterials. They treat infections by eliminating or inhibiting bacterial proliferation. In 1936, the first modern antibiotic was used. Before the discovery of antibiotics, 30 percent of all fatalities in the United States were due to bacterial infections. Thanks to antibiotics, infections that were once fatal are now curable.

Antibiotics are still potent, life-saving medications for individuals with certain severe infections. Additionally, they can prevent less severe infections from becoming critical.

The purpose of medicines is to mitigate symptoms, not to exacerbate them. Unfortunately, a few medications actually make the situation worse. Doxycycline is one of these medications that doxycycline ruined my life rather than cured my illness.  There are numerous antibiotic classifications. Antibiotics are most effective against specific forms of bacterial infections.

What are Antibiotics Made of?

Accidentally, the first beta-lactam antibiotic, penicillin, was discovered. Mold in a petri dish gave rise to the organism. Scientists discovered that a particular species of fungus produced penicillin naturally. Eventually, significant quantities of penicillin were produced in a laboratory by fermenting the fungus.

Other early antibiotics were produced by microbes found on the earth’s surface.

Today, every antibiotic medication is manufactured in a laboratory. Some are produced through a series of chemical reactions that yield the active ingredient.

At least a portion of other antibiotics are produced through a natural but regulated process. This process is frequently augmented by chemical reactions that transform the original substance into a new medication.

How do Antibiotics Work to Kill Bacteria?

Antibiotics function by interfering with the bacterial cell wall to prevent bacterial growth and replication. Many varieties of bacteria have cell walls, but human cells do not; therefore, antibiotics can target bacteria without harming human cells.

Antibiotics are either bactericidal (they destroy the bacteria) or bacteriostatic (they prevent the reproduction and growth of bacteria).

Antibiotics have no effect on the viruses that produce the common cold, influenza, and numerous coughs, so they are ineffective against these conditions.

Side Effects

Due to the presence of both good and harmful bacteria in the digestive tract, antibiotics frequently affect the digestive system when treating an infection. Typical adverse effects include:

  • Vomiting
  • Nausea
  • Diarrhea
  • Bloating or indigestion
  • Abdominal pain
  • Loss of appetite

Occasionally, you may exhibit additional symptoms, such as:

  • Hives – a raised, itchy skin rash
  • Coughing
  • Wheezing
  • Tight throat or trouble breathing

If you experience these symptoms, it is possible that you are allergic to your antibiotic; therefore, you should contact your doctor immediately.

Antibiotics may impair the efficacy of birth control tablets, so if you are taking them, discuss with your doctor whether alternative birth control methods might be preferable. Antibiotics can also cause vaginal yeast infections in women. The symptoms include irritation, burning, vaginal discharge (that resembles cottage cheese), and sexual discomfort. The condition is treated with an anti-fungal ointment. Apart from it, do you know- can diverticulitis cause hip and leg pain? You have to be aware of it always too. 

Interactions

Individuals taking antibiotics should not take other medications or herbal supplements without first consulting a physician. Certain over-the-counter drugs may also interact with antibiotics.

Some physicians believe that antibiotics can diminish the efficacy of oral contraceptives. However, research generally does not corroborate this.  Those who experience diarrhea and vomiting or who do not take their oral contraceptive during illness due to an irritated stomach may notice a decrease in its efficacy.

In such cases, physicians may advise patients to take additional contraceptive measures. Doctors may also recommend avoiding alcohol with certain medications. Doxycycline is one of these medications that may have destroyed my life. However, moderate alcohol consumption is unlikely to interfere with the majority of antibiotics.

How Long Do Antibiotics Take to Work?

Depending on the illness, antibiotics typically show improvement against bacterial infections within one to three days. Some of the symptoms are caused by your body’s immune response, so you may not feel better immediately. It may take time for your immune system to return to normal once detrimental bacteria have been eliminated.

Patients must take antibiotics for seven to fourteen days. However, in some instances, shorter treatments can also be effective. The duration of treatment depends on the length of treatment and the variety of antibiotics prescribed by the physician. Even though you may feel better after a few days of treatment, it is best to complete the entire course to effectively treat your infection. Otherwise, you may contribute to the spread of bacteria resistant to antibiotics.

Why are Antibiotics Important?

Antibiotics introduced to medicine revolutionized the treatment of infectious diseases. Between 1945 and 1972, the average human life expectancy increased by eight years due to the use of antibiotics to treat previously fatal infections. Antibiotics are one of the most widely used classes of drugs in modern medicine, and they enable many of the complex operations that have become routine around the globe.

If we ran out of effective antibiotics, it would set back modern medicine by decades. Prior to the widespread use of antibiotics, relatively minor surgical procedures, such as appendectomies, could pose a life-threatening risk. Antibiotics are sometimes administered to a small number of patients prior to surgery to prevent infections caused by bacteria invading open wounds. Without this precaution, the risk of blood poisoning would be significantly increased, and many of the complex surgeries currently performed by physicians may no longer be possible.

 

Image Credit: Photo by Roberto Sorin on Unsplash